Perhaps one of the greatest contributions made by Lupton Patten was the modernization and expansion of the Company's research facilities. In addition, consultants from 24 universities, hospitals and private laboratories engaged in research projects for the Company. Soon Dr. John C. Krantz discovered one of the first new antacid compounds commonly known as Dihydroxy Aluminum Aminoacetate while conducting research for the Company. Shortly thereafter, Dr. Irvine W. Grote, a Company advisor, discovered a second new antacid, Dihydroxy Aluminum Sodium. These two compounds were manufactured by the fine chemicals division until recently for use in "Bufferin" and "Rolaids", respectively.